Sugar - as a skincare ingredient it has water-binding properties, which means that it helps to keep your skin nice and hydrated. If you also wish to buy as a one time purchase please make 2 separate checkout transactions. Gluten Free, Vegan, and Oncology Friendly, iS Clinical Moisturizing Complex (1.7 oz.) Complimentary gift will be awarded at the cart. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol. I think over time it has really helped even out my skin tone while keeping my 40 year old skin hydrated and smooth. Learn more about klarna_slice Its a yellowish powder with a nice sweet smell. Use the enter key to expand submenu items. Learn More about afterpay A handy white powder that magically converts a liquid into a nice gel formula. Hexylene Glycol is also part a preservative blend namedLexgard HPO, where it helps the effectiveness of current IT-preservative, phenoxyethanol. 0 Hello! Where reviews refer to foods or cosmetic products, results may vary from person to person. It also forms a protective barrier on the skin and fills in fine lines. The numberin the name ofCeteareth emulsifiers refersto the average number of ethylene oxide molecules added and 20 makes a good emulsifier. Learn more, 4 installments of $58.75 with If possible use it at night, just to be on the safe side. Item already in basket as a one time purchase. And that is still not all: it can also boost the antimicrobial activity of preservatives. A famous natural moisturizing factor that can bind up to 1000 times its own weight in water. Shop our Summer Sale and save 10% when you use code "SUMMERSKIN10", Sodium Hyaluronate - Please try making an alternative selection. It has a high affinity for copper ions and likes to form a complex with them called Copper-Tripeptide-1 or GHK-Cu. I wake up with my skin feeling great! It acts asa mild keratolytic agent(some of its moisturizingaction is thought to come from urea's abilityto break down bonds in the protein called filaggrin and thus freeing up amino acids in the skin), enhancesantimicrobial peptide expression and improvesskin barrier function. They hypothesize that "EUK-134, via direct protection of the membrane from UVB-induced oxidative damage, reduces oxidative stress induced MAPK signaling and consequently lowers the level of p53 induction. Its mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. Klarna E-Commerce Software & Design by Endertech in Los Angeles. *Results based on 4-week clinical study conducted by BioScreen Clinical Service, 100% increase in skin hydration in one day*, 77% increase in skin firmness in four weeks*. Please try again. It has a water-lovinghead with two water-hatingtails and this structure gives the molecule emulsifying properties. Water/Aqua/Eau, Hyaluronic Acid, Caprylic/Capric Triglyceride, Vaccinium Myrtillus Fruit/Leaf Extract, Glycerin, Urea, Glucose, Guanidine HCI, Tripeptide-1, Saccharum Officinarium (Sugar Cane) Extract, Salix Alba (Willow) Bark Extract, Glyceryl Dilaurate, Tetrahexyldecyl Ascorbate, Dimethicone, Cetyl Alcohol, Dipalmitoyl Hydroxyproline, Superoxide Dismutase, Ormenis Multicaulis Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Phospholipids, Retinyl Palmitate, Tocopheryl Acetate, Pnatothentic Acid, Acer Saccharum (Sugar Maple) Extract, Citrus Aurantium Dulcis (Orange) Fruit Extract, citrus Medica Limonum (Lemon) Fruit Extract, Asiaticoside, Asiatic Acid, Madecassic Acid, Asorbyl Palmitate, PEG-8/SMDI Copolymer, Dipotassium Glycyrrhizte, Soy Isoflavones, Ethylbisminomethylguaiacol Maganese Chloride, Hexylene Glycol, Ethylhexyl Palmitate, Silica Demethyl Silylate, Butylene Glycol, Cetearyl Alchol, Ceteareth-20, glyceryl Stearate, PEG-100 Stearate, Carbomer, Xanthan Gum, PVP, Panethnol, Triethanolamine, Disodisum EDTA, Caprylyl Glycol, Methylglucoside, Phosphate, Copper Lysiante/Prolinate, 1, 2-Hexanediol. Bottom line: a really promising, but not well-proven vitamin C derivative that can be worth a try especially if you like experimenting (but if you likethe tried and true, pure vitamin Cwill be your best bet). Customer reviews are independent and do not represent the views of The Hut Group. It's a really promising candidate (see below), but while reading all the goodness about it in a minute, do not forget that derivatives not only haveto be absorbed into the skin but also have to beconverted to pure vitamin C (ascorbic acid or AA) and the efficacy of the conversion is often unknown. In general, the main component of citrus peel oils is limonene(83-97% for sweet orangepeel), a super common fragrant ingredient that makes everything smell nice (but counts as a frequent skin sensitizer). It is there in lots of products in tiny amounts (honestly, we do not really understand why), however, we do not know about any vitamin C serum featuring AP in high amounts. Typically used at 1% or less in most formulations. Far surpassing its other anti-aging, age-defying treatment counterparts, this transformative cream scientifically combines the purest and most effective botanically-derived moisturizers, antioxidants, resurfacing acids and growth factors to help reduce the appearance of fine lines and wrinkles through powerful hydration.. Clinically proven to show visible results in smoother skin and a firmer and more radiant, youthful complexion, this extraordinarily complex cream not only restores moisture into the skin but provides potent antioxidant protection and increases visible collagen production. I use this every night and my skin feels so smooth and refreshed. The manufacturer claims that the complex is able to boost skin's own collagen I and III as well as elastin production. A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquidinto a nice gel formula. Advanced Anti-Aging, Tightening & Hydration. Also known as Sugarcane, Saccharum Officinarum is a handy moisturizing ingredient mostly used as a humectant. In addition,vitamin C's three magic properties (antioxidant, collagen booster, skin brightener) are all properly proven in-vivo (on real people), but for the derivatives, it's mostly in-vitro studies or in thecase of ATIP, it's in-vitro and done by an ingredient supplier. ), 4 installments of $58.75 with Apply a small amount to clean skin, smoothing over face and neck (or as directed). Learn More, 4 installments of $58.75 with We will notify you when it becomes available! The retinoid family is pretty much the royal family of skincare, with the queen being the FDA-approved anti-aging ingredient tretinoin. It is also often used to create liposomes, small spheres surrounded by phospholipid bi-layer designed to carry some active ingredient and helpits absorption. This transformative crme scientifically combines the purest and most effective botanically-derived moisturizers, antioxidants, resurfacing acids, and growth factor. The main reason it is used in skin care is that it contains natural AHA acids, namely Malic and Tartaric, and hence why itsupposedly helps slough off dead skin cells in combination with other acid-containing fruit extracts as part of the trade name ACB Fruit Mix. Learn More, 4 installments of $58.75 with So now, you know that Vitamin C is great and all, but it's really unstable and gives cosmetics companies many headaches. For the best experience on our site, be sure to turn on Javascript in your browser. Thanks. months. A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth. It's also often used to create liposomes. To solve this problem they came up with vitamin C derivatives, and one of them is Tetrahexyldecyl Ascorbate (let's call it ATIP in short). Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-calledrheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). reward points when purchasing this product as a rewards member*. A great study in the Journal of Cosmetic Dermatology compared a bunch of vitamin C derivatives and this derivative was the only one where the study said in terms of stability that it's "similar to AA". Normal (well kind of - it's purified and deionized) water. Plus, receive a gift when you spend $175+ on the brand. These three letters stand for Poly Vinyl Pyrollidone, a big molecule created from repeated units of Vinyl Pyrrolidone, aka VP. ). Preserving your skin is an ongoing process, just like going to the gym. Usually dispatched within 24 hours, 4 installments of $58.75 with Similar to other glycols, it's a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thickliquid. We'll get back to you as soon as possible. Waxy, white, solid stuff that helps water and oil to mix together and leaves the skin feeling soft and smooth. This is the reason why hair styled with a PVP based product loses its style in high humidity. Clinically proven to help diminish the appearance of premature aging and visibly reduce wrinkles over time. If you are into Gotu Kola we have some more info at Centella Asiatica Extract and its other biologically active components. And in the skin. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. Learn More, 4 installments of $58.75 with I use it at night and wake up so hydrated and smooth. ), Rewards members get DOUBLE points on SkinCeuticals. Its approved by Ecocert and also used in the food industry(E415). Superoxide Dismutase - or in short SOD - is the body's smart antioxidant enzyme that protects the cells from highly reactive, cell-damagingsuperoxide radicals (O2). The manufacturer claims that both malic and tartaric increase elasticity in the skin,but from our research, the only confirmed uses of these acids are as pH adjusters, especially in the tiny amounts they can be found in the Fruit Mix (less than 1%). Second, because it's oil-soluble, its skin penetration abilities seem to be great. An essential amino acid - mineral complex that is part of the pretty new anti-aging complex called Neodermyl. If the product is too runny, a little xanthan gum will make it more gel-like. 15%, 15% off initial purchase and 15% savings on future replenishment orders, iS Clinical Cleansing Complex (6 fl. Learn more, 4 installments of $58.75 with When I first started using it I was using Kinerase (which I thought was doing a good job) I noticed after I started using this product my skin was less flakey and more even tones and smooth. Amazing product! Apply a small amount to clean skin, smoothing over face and neck (or as directed). afterpay Water/Aqua/Eau, Hyaluronic Acid, Caprylic/Capric Triglyceride, Vaccinium Myrtillus Fruit/Leaf Extract, Glycerin, Urea, Glucose, Guanidine HCl, Tripeptide-1, Saccharum Officinarum (Sugar Cane) Extract [Extrait de canne sucre], Salix Alba (Willow) Bark Extract, Glyceryl Dilaurate, Tetrahexyldecyl Ascorbate, Dimethicone, Cetyl Alcohol, Dipalmitoyl Hydroxyproline, Superoxide Dismutase, Ormenis Multicaulis Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Phospholipids, Retinyl Palmitate, Tocopheryl Acetate, Pantothenic Acid, Acer Saccharum (Sugar Maple) Extract, Citrus Aurantium Dulcis (Orange) Fruit Extract, Citrus Medica Limonum (Lemon) Fruit Extract, Asiaticoside, Asiatic Acid, Madecassic Acid, Ascorbyl Palmitate, PEG-8/SMDI Copolymer, Dipotassium Glycyrrhizate, Soy Isoflavones, Ethylbisiminomethylguaiacol Maganese Chloride, Hexylene Glycol, Ethylhexyl Palmitate, Silica Dimethyl Silylate, Butylene Glycol, Cetearyl Alcohol, Ceteareth-20, Glyceryl Stearate, PEG-100 Stearate, Carbomer, Xanthan Gum, PVP, Panthenol, Triethanolamine, Disodium EDTA, Caprylyl Glycol, Methylglucoside Phosphate, Copper Lysinate/Prolinate,1,2-Hexanediol. With thiscontext in mind let's see whatATIP might be able to do. Learn More, 4 installments of $58.75 with This is a favorite! Some essential oil content is usually also present in citrus fruit extracts, which means a nice scent and antibacterial properties, but also some questionable compounds such as fragrance allergenlimoneneor phototoxic compoundbergaptene. It's readily biodegradable. Its a yellowish powder with a nice sweet smell. It's a water-hating, fumed silica that works as a thickener for oils and it can also suspend particles in oils. A stable, oil-soluble form of Vitamin C, that might have (in-vitro results) all the magic abilities of pure vitamin C (antioxidant, collagen booster, skin brightener). As for the hair the hydration effect is also true there. We wrote some more about SOD here. Regarding the skin-brightening properties of pure vitaminC, this is another magic property AP does not have, or at least there is no data, not evenin-vitro,about it. This means that it can help the skin to attract water and then to hold onto it. Apart from soothing salicin, it also containsflavonoids and phenolic acids that give willow bark tonic, astringent, and antiseptic properties. I have used it for many years and love it! We do a Best of INCIDecoder email once a month with the most interesting products and ingredients we bump into. It does not have the very best safety reputation but in general, you do not have to worry about it. Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) Apply a small amount to clean skin, smoothing evenly over face and neck (or as directed). A small, three amino acid (glycine-histidine-lysine or GHK) peptide that is famous for being atype I collagen fragment. To fix this problem, there are now several versions of VP containing film formers that are less sensitive to humidity, for example, the molecule called VP/VA Copolymer. Third, another study that wanted to examine the antioxidant properties of AP was surprised to find that even though AP does have nice antioxidant properties;following UVB radiation (the same one that comesfrom the sun) it also promotes lipid peroxidation and cytotoxicity. The disadvantage of PVP is that the film is a bit brittle and that PVP loves water (hygroscopic) that tends to destroy the film. It can be a replacement for mineral oil and is often combined with other emollients to achievedifferent sensorial properties. But orange fruit is loaded with lots of other active compounds with a wide variety of possible effects. So this unpronounceable guy is actually anice molecule that mimics the behavior of the natural enzymes in our skin. To complicate matters further, there are lots of varieties and lots of extraction methods, so it is a bit hard to know what you are gettingwith this one, but we will try our best to summarize the possibilities. Product packaging may differ from image due to occasional manufacturer changes. I have been using multiple iSClinical products for about 6 years now. It also has tonic, astringent, and antiseptic properties. sezzle Luckily when you put it on your skin it's good for you not like when you eat it. Sorry, there seems to have been an error. Can be derived from coconut or palm kernel oil. An essential amino acid - mineral complex that is part of the pretty new anti-aging complex called Neodermyl. It's a popular duo. Overall, just like glycerin, urea is a real oldie but a goodie, a nice ingredientin anymoisturizer. So PVP likes to attach itself to surfaces such as the hair and the skin and forms a nice, thin, even film there. The most well-known one isgenistein, a potent antioxidantthat is proven to inhibit UV-induced rednessin human skin. So this all sounds really great, but these are only in-vitro results at this point. Flavonoids(hesperidin, naringin, luteolin, and ferulic acid) are also nice active compounds with possible antioxidant, anti-inflammatory, and vasoprotective effects. Skincare can be confusing! Its a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols. It was only an in-vitro study meaning that it was done on cellcultures and not on real people, but still, this also does not support the use of AP too much. This does not mean thatascorbyl palmitate cannot penetrate the skin (because it can, it's oil soluble and the skin likes to absorb oil soluble things) but this means that it's questionable ifascorbyl palmitate can be converted into pure Vit C in the skin. It's great as night-cream since it promotes cellular turnover, but it's nice in the morning as well! However, it is hard to know how much pure vitamin C or ATIP can be thanked. If that wasnt enough panthenol is also useful in nail and hair care products. Our goal is to help maintain your skin to ensure that it is looking beautiful, vibrant, and full of the youthful, healthy glow we all desire. Englishtranslation equals thatit probably contributes to the well-established moisturizing and wound healing abilitiesof Gotu Kola. Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid calledstearic acid. Soy isoflavones are also thought to be useful for situations when natural estrogen levels are low, such as during and after menopause. A super common, medium-spreading emollient ester that gives richness to the formulaand a mild feel during rubout. JavaScript seems to be disabled in your browser. It was the first synthetic polymer introduced as a hair fixative in the 1950s instead of insect-derivedShellac. Its a humectant meaning that it can help the skin to attract water and then hold onto it. Sign up to our email list and receive 20% off your next order, Meet Our 2021 Experts' Choice Awards Winners: Round 1. Choosing a selection results in a full page refresh. However, if you use a product that you like and it also contains RP, there is no reason to throw it away. iS Clinical Youth Intensive Crmeis an extremely powerful moisturizing cream for long-term hydration and anti-aging effects. Once open, most effective when used within 12 months. What is true is that if a product contains so-called N-nitrogenating agents (e.g. A super common, medium-spreading emollient ester that gives richness to the formulaand a mild feel during rubout. Its anti-aging effects are quite questionable as well as its behavior in the presence of UVA light. It has well established wound healing and antioxidant activities. :) It has water-binding properties, which means that it helps to keep your skin nice and hydrated. Both slow down with ageand beeing able to boost the skin's own production of these super important proteins results in improved skin firmness and elasticity. Like this, the products can stay more stable over time. Its main component (83-97%) is limonene, the super common fragrant ingredient. For best results, follow complete IS CLINICAL skincare regime. Other than that, we found a study that examined a serum to manage skin redness in sensitive, pale skin types and contained EUK-134 along with a bunch of other ingredients. It's part of an anti-aging complex trade named Neodermyl, where methylglucosidephosphate is combined with the essential amino acids proline, lysine and also copper. In-vitro (made in the lab) studies also show thatAsiaticosidestimulates GAGs (glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells) production as well as collagen I synthesis. The essential oil coming from the rind of the orange (thesweetone). It seems that there is a study showing RP being photo protective against UVB rays but there is also a study showingRP causing DNA damage and cytotoxicity in association with UVA. "This super-rich anti-aging cream provides everything aging skin needs: moisture, antioxidants, resurfacing acids, and growth factors.". One of the biologically active componentsof Gotu Kola. Learn more. For best results follow complete IS CLINICAL skincare regimen.Once open, most effective when used within 12 months. Depending on your hair type, it can bea bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types). It helps to soften scars and increase their elasticity. Another reason whyTripeptide-1 is especiallyfamousis that it is not only a signal peptidebut also a so-called carrier peptide thathelps to stabilize and deliver copperin the skin. A form of skincare superstar, vitamin C.Even though we are massive vitamin C fans, Ascorbyl Palmitate (AP) is our least favorite. The thing in the pee that is also a natural moisturizing factor (NMF) with mild keratolytic and strong skin moisturizing superpowers. But there is nothing better. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily. Its a great pick for creating a nice feeling product. Antioxidant-rich natural enzyme that helps protect against the visual effects of photodamage while supporting healthy skin, uniquely designed for skin absorption. If you are wondering what the heck SOD and catalase are, here is a little background: Similar to other glycols, it's a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable. afterpay An easy-to-formulate, commonly used, nice to have ingredient thats also called pro-vitamin B5. Good old water, aka H2O. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier. zip An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. Another study (also by Estee Lauder) found that EUK-134 lowers hydroperoxide levels at the surface of UVA-exposed skin in vivo and concluded that this salenmanganese compoundis a "unique cosmetic tool to protect the skin surface from accumulating oxidative damage". Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. You can read all about the pure form here.